● Aldosterone low Iead to hyponatremia , hyperkalemia and decrease excretion of H ( metabolic acidosis ). ● PRA high ● Cortisol low ● Androgen hormones high lead to ambigous genitalia.
2. 17- hydroxylase deficiency
● Aldosterone high Iead to hypernatremia, hypertension , hypokalemia and increas excretion of H ( metabolic alkalosis). ● Cortisol low ● Androgen hormones low
3. 11-β-Hydroxylase Deficiency ● Aldosterone low compensated by DOC lead to hypokalemia, hypernatremia or nornal and hypertension . ● PRA low( due to retention of water ) ● Cortisol low . ● Androgen hormones high lead to ambigous genitalia.
