Case study : A 45‐year‐old shop assistant presented to her GP | Biochemistry

Case study :
A 45‐year‐old shop assistant presented to her GP
complaining of fatigue, weight gain, trouble sleeping, anxiety and hot flushes. Her periods were regular.
Her hormone profile was as follows, with the sample taken at day 3 of her menstrual cycle.

Laboratory results :
●Prolactin 500 (<500mU/L )
●LH 9.0 (2.0–9.0U/L )
●FSH 25 (2.0–10.0U/L )
●estradiol 120 75-140 pmol/L
●TSH 3.5 ( 0.2–4.5mU/L )
●FT4 12 ( 9–21pmol/L.)

How would you interpret these results in light of the
history and clinical findings?