Beta-blockers e.g. bisoprolol should not be used with verapami | MedicoQz
Beta-blockers e.g. bisoprolol should not be used with verapamil due to the risk of bradycardia, heart block, congestive heart failure. This is a typical angina history. Beta-blocker is a first line Angina prophylaxis. However, this man is taking verapamil for his migraine. Verapamil should not be used with beta blocker due to the risk of bradycardia, heart block or even congestive cardiac failure. Therefore, bisoprolol and metoprolol are incorrect answers. Ibuprofen and digoxin do not reduce the frequency of angina. Therefore, the next line for prophylaxis of angina is Nicorandil.