MedRophine Science

2022-05-08 21:17:59 Good Case:
Right sided auricular necrosis. Failure of repairing pinna avulsion after motor vehicle accident (MVA) trauma. While the primary failure signs including color change was obvious within just 3 days after reconstruction, it was neglected by the patient for about 30 days! باز کردن / نظر دهید

2022-05-06 13:48:52 Renal Nutcracker Syndrome باز کردن / نظر دهید

2022-05-06 11:38:25 This two-front strategy effectively treated several highly aggressive TNBC primary tumours and metastasis. The study appeared in the journal Cancer Research.
“TNBC is an aggressive subtype of breast cancer with an overall poorer prognosis than other breast cancer subtypes,” said co-corresponding author Dr. Jeffrey Rosen, Distinguished Service Professor of molecular and cellular biology and in the Dan L Duncan Comprehensive Cancer Center at Baylor.
The team had previously shown in animal models that although treating the tumours with cyclophosphamide eliminated the cancer initially, the disease came back eventually. A closer look into the tumour microenvironment revealed that the tumours that returned typically had many macrophages.
“In this study, we explored the possibility that eliminating both the tumour cells and the macrophages would improve the chances of eliminating the tumour for a longer period of time,” said Swarnima Singh…
You can read very useful information about this article in comments: باز کردن / نظر دهید

2022-05-06 11:36:12 Hot News:(28 Apr 2022)

A promising combination therapy for triple-negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions have identified a combination therapy for treating triple-negative breast cancer (TNBC) that results in durable tumour regression in an animal model of the condition.
The combination therapy attacked the tumour on two fronts. On one side, the chemotherapy drug cyclophosphamide eliminated tumour cells, while on the other front, another drug inhibited tumour-associated cells called macrophages, which block the body’s immune response against the tumour. باز کردن / نظر دهید

2022-05-04 14:10:06 Case report :

A primiparous 26-year-old patient, with unremarkable personal medical history,but her sister had esophagus atresia associated with situs inversus and primary ciliary dyskinesia.

The first-trimester ultrasound screening at 12 weeks and 4 days of gestation revealed a hyperechoic aspect of the entire right lung, which led doctors to suspect a unilateral pulmonary pathology . Nuchal translucency was measured at 0.9 mm for a cranio-caudal length at 62.5 mm.(measured NT value is 8 percentile for this CRL) . Just for reminding the fact that normal or lower than normal NT doesn’t mean that a fetus is completely healthy!

Pregnancy terminated and the histology of the right lung showed multiple cysts relatively uniform in size,..etc and a pathological diagnosis of CCAM type 3 was confirmed. باز کردن / نظر دهید

2022-05-04 12:23:34 Cystic adenomatoid malformation type 2 :

Axial image of the chest demonstrating an echogenic mass(arrows) containing small cysts displacing the heart(arrowhead)to the right. باز کردن / نظر دهید

2022-05-04 12:22:45 A CCAM is a benign mass of abnormal lung tissue that replaces part of one lobe of a fetal lung. CCAMs can occur in either lung and are classified into three different types based on the size of the cyst or cysts. The prognosis for most fetuses diagnosed… باز کردن / نظر دهید

2022-05-04 12:22:09 A CCAM is a benign mass of abnormal lung tissue that replaces part of one lobe of a fetal lung. CCAMs can occur in either lung and are classified into three different types based on the size of the cyst or cysts.

The prognosis for most fetuses diagnosed with CCAMs is excellent, though the condition must be closely monitored. In a small percentage (approximately 10%) of cases, the CCAM can grow large enough to become life threatening during pregnancy. In those cases, the fetus may develop hydrops, a condition in which fluid is collected in the chest cavity signaling heart failure.

As mentioned the prognosis is usually optimal. Poor prognostic findings are hydrops fetalis, ascites, polyhydramnios, bilateral lung involvement, and a final lung-to-thorax transverse area ratio of less than 0.25 , or the cystic adenomatoid malformation volume ratio—which is defined as the estimated volume of the CCAM divided by head circumference—is used to predict prognosis. A ratio >1.6, leads to a poorer prognosis.

Genetic counseling is necessary and pregnancy termination is frequently wrongly proposed due to “poor prognosis.” ! The good prognosis could be explained by the fact that the cyst decreases in size in utero in the majority of cases. باز کردن / نظر دهید

2022-05-04 11:31:57 Congenital cystic adenomatoid malformation

A congenital cystic adenomatoid malformation appears sonographically as unilateral pulmonary mass with one of the following characteristics:

Type 1: a mass with one or more large cysts.

Type 2: an echogenic mass containing small
cysts.

Type 3: a homogeneously echogenic mass .


Images :

Cystic adenomatoid malformation type 1.

A: Axial image of chest demonstrating large echogenic mass (arrows) with a large cyst(*). The mass fills the right hemithorax, displacing the heart (arrowhead) to the left.

B: Sagittal image of right chest showing the large mass (arrows) containing the cyst(*) باز کردن / نظر دهید

2022-05-04 11:26:53 38 year old lady was in a motor vehicle collision about 6 weeks ago - she T-boned a car at about 60 mph, taken to ER and no radiographs were taken. There are no current complaints of the neck region. What is your diagnosis?
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Case courtesy of Darren Sealey DC, Marion, South Carolina باز کردن / نظر دهید